Name | p-Anisic acid |
Synonyms | anisic acid p-Anisic acid para-anisic acid 4-methoxybenzoate Methoxybenzoic acid P-methoxybenzoic acid 4-Methoxybenzoic Acid Benzoic acid, methoxy- P-anisic acid crystalline melting point standard P-anisic acid bis[2-[[(p-methoxyphenyl)methylhydrazono]methyl]-1,3,3-trimethyl-3H-indolium] carbonate |
CAS | 100-09-4 1335-08-6 |
EINECS | 215-618-8 |
InChI | InChI=1/C8H8O3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3,(H,9,10) |
Molecular Formula | C8H8O3 |
Molar Mass | 152.15 |
Density | 1.208g/cm3 |
Melting Point | 181-186℃ |
Boling Point | 278.305°C at 760 mmHg |
Flash Point | 115.46°C |
Solubility | Soluble in ethanol, ether, chloroform and ethyl acetate, soluble in 2500 parts of water, slightly more soluble in hot water. |
Vapor Presure | 0.002mmHg at 25°C |
Appearance | Colorless needle crystal |
Storage Condition | Room Temprature |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.546 |
MDL | MFCD00002542 |
Physical and Chemical Properties | Properties colorless needle-like crystals solubility: soluble in ethanol, ether, chloroform, slightly soluble in hot water, insoluble in cold water. |
Use | It can be used as a pharmaceutical intermediate such as soleracetam and ethylaminosulfonone, and can also be used for spices. |
Safety Description | S24/25 - Avoid contact with skin and eyes. |
Reference Show more | 1. Zhang Jian, Zheng Jinghui, Gao Chenghai, Lin Yu, Li Xuejian, Feng Yuyan, Zheng Xueying, Yin Jianglin. Optimization of Fermentation Conditions for Anisic Acid Producing Bacteria [J]. Industrial Microbiology, 2021,51(02):22-30. 2. Zhang Jian, Zheng Jinghui, Gao Chenghai, Lin Yu, Li Xuejian, Feng Yuyan, Zheng Xueying, Yin Jianglin. Optimization of Fermentation Conditions for Anisic Acid Producing Bacteria [J]. Industrial microorganism, 2021,51(02):22-30. 3. [IF = 7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples." FOOD CHEMISTRY. 2022 Oct;390:133155 |
colorless needle-like crystals, soluble in ethanol, ether, chloroform, micro-soluble in hot water, insoluble in cold water.
p-Hydroxybenzoic acid was obtained by reaction with dimethyl sulfate.
used as a raw material for preservatives, medicines and fragrances.
Usage:
Methoxybenzoic acid is an important intermediate in organic synthesis. It can be used for dyes and other chemicals. In addition, it also has applications in the rubber industry.
Preparation Method:
Methoxybenzoic acid has a variety of preparation methods. Among them, a commonly used method is to react methyl phenyl methyl ether with an oxidizing agent to produce methoxy benzoic acid. This process is actually a step in the oxidation of toluene.
Safety Information:
Methoxybenzoic acid may cause irritation and injury when exposed to the skin, eyes or by inhalation. During use, appropriate protective measures should be taken, such as wearing protective glasses, gloves and masks. In addition, it should be ensured that the operation is carried out in a well-ventilated place to avoid inhaling its smell or dust. If you come into contact with methoxybenzoic acid, rinse the affected area immediately with plenty of water and consult a professional doctor for advice.